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Keishi Miyata Selected Research

Angiopoietin-Like Protein 2

1/2021Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis.
12/2019Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity.
1/2018Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction.
1/2017ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis.
2/2016Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.
1/2016Macrophage-Derived Angiopoietin-Like Protein 2 Exacerbates Brain Damage by Accelerating Acute Inflammation after Ischemia-Reperfusion.
1/2016Mice Deficient in Angiopoietin-like Protein 2 (Angptl2) Gene Show Increased Susceptibility to Bacterial Infection Due to Attenuated Macrophage Activity.
3/2015ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling.
9/2014Serum ANGPTL2 levels reflect clinical features of breast cancer patients: implications for the pathogenesis of breast cancer metastasis.
5/2014Diverse roles of ANGPTL2 in physiology and pathophysiology.
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Keishi Miyata Research Topics

Disease

18Inflammation (Inflammations)
01/2018 - 09/2009
17Obesity
11/2021 - 04/2005
9Neoplasms (Cancer)
01/2022 - 10/2003
6Neoplasm Metastasis (Metastasis)
01/2018 - 12/2011
5Atherosclerosis
11/2021 - 01/2009
4Atherosclerotic Plaque (Atheroma)
11/2020 - 01/2009
4Metabolic Diseases (Metabolic Disease)
01/2018 - 05/2010
4Insulin Resistance
04/2013 - 04/2005
3Carcinogenesis
01/2022 - 12/2011
3Heart Failure
01/2021 - 01/2018
3Hyperplasia
04/2013 - 04/2005
2Fatty Liver
11/2021 - 04/2014
2Rupture
11/2020 - 10/2010
2Hypoxia (Hypoxemia)
11/2020 - 01/2018
2Muscular Atrophy (Muscle Atrophy)
01/2019 - 01/2018
2Osteosarcoma (Osteogenic Sarcoma)
01/2018 - 01/2014
2Mitochondrial Diseases (Mitochondrial Disease)
01/2018 - 03/2015
2Fibrosis (Cirrhosis)
10/2016 - 02/2016
2Ischemia
01/2016 - 05/2008
2Rheumatoid Arthritis
01/2016 - 05/2010
2Breast Neoplasms (Breast Cancer)
03/2015 - 09/2014
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2014 - 12/2011
1Colorectal Neoplasms (Colorectal Cancer)
01/2022
1Intestinal Neoplasms (Intestinal Cancer)
01/2022
1Thrombocytopenia (Thrombopenia)
12/2021
1Cardiogenic Shock
12/2021
1Hyperglycemia
12/2021
1Myocardial Infarction
12/2021
1Dyslipidemias (Dyslipidemia)
11/2021
1Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
11/2021
1Premature Aging
01/2020
1Weight Gain
01/2020
1Renal Cell Carcinoma (Grawitz Tumor)
06/2019
1Kidney Neoplasms (Kidney Cancer)
06/2019
1Hypertrophy
01/2019
1Autism Spectrum Disorder
01/2018
1Sarcopenia
01/2018
1Autistic Disorder (Autism)
01/2018
1Cardiovascular Diseases (Cardiovascular Disease)
01/2018
1Cachexia
01/2017
1Weight Loss (Weight Reduction)
01/2017
1Psoriasis (Pustulosis Palmaris et Plantaris)
10/2016
1Interstitial Lung Diseases (Interstitial Lung Disease)
10/2016
1Chronic Renal Insufficiency
02/2016

Drug/Important Bio-Agent (IBA)

21Angiopoietin-Like Protein 2IBA
01/2021 - 09/2009
12Proteins (Proteins, Gene)FDA Link
06/2019 - 10/2003
6Messenger RNA (mRNA)IBA
01/2020 - 01/2009
5CytokinesIBA
01/2016 - 05/2010
4Apolipoproteins E (ApoE)IBA
11/2021 - 02/2009
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2018 - 04/2005
3Angiopoietin-like ProteinsIBA
01/2018 - 04/2012
3Insulin (Novolin)FDA Link
01/2018 - 01/2013
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2016 - 04/2013
3Transcription Factor CHOPIBA
09/2015 - 10/2010
3AngiopoietinsIBA
05/2008 - 10/2003
2Blood Glucose (Blood Sugar)IBA
12/2021 - 01/2020
2Triglycerides (Triacylglycerol)IBA
11/2021 - 04/2014
2CholesterolIBA
11/2021 - 10/2010
2ApolipoproteinsIBA
11/2020 - 04/2014
2Matrix Metalloproteinases (MMPs)IBA
11/2020 - 01/2014
2Bleomycin (Blenoxane)FDA LinkGeneric
10/2016 - 09/2015
2EnzymesIBA
01/2016 - 01/2014
2LipidsIBA
01/2009 - 04/2005
2HydrolasesIBA
01/2008 - 04/2005
1osteoblast cadherinIBA
01/2022
1CateninsIBA
01/2022
1EpitopesIBA
11/2021
1VaccinesIBA
11/2021
1Protein Subunit VaccinesIBA
11/2021
1Angiopoietin-Like Protein 3IBA
11/2021
1Peptides (Polypeptides)IBA
11/2021
1oxidized low density lipoproteinIBA
11/2021
1LDL CholesterolIBA
11/2021
1CarcinogensIBA
01/2021
1Long Noncoding RNAIBA
01/2021
1FebuxostatFDA Link
11/2020
1Xanthine OxidaseIBA
11/2020
1gnemonoside AIBA
01/2020
1gnetin CIBA
01/2020
1Biomarkers (Surrogate Marker)IBA
06/2019
1MicroRNAs (MicroRNA)IBA
06/2019
1HMGB2 ProteinIBA
01/2019
1TaurineFDA Link
01/2018
1Interleukin-6 (Interleukin 6)IBA
01/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2018
1neuregulin-4IBA
01/2018
1EGF Family of ProteinsIBA
01/2018
1Monoclonal AntibodiesIBA
01/2018
1ChromatinIBA
01/2018
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2018
1Transfer RNA (tRNA)IBA
01/2018
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
01/2018
1Sodium-Glucose Transporter 2 InhibitorsIBA
01/2017

Therapy/Procedure

6Therapeutics
12/2021 - 05/2010
2Denervation
01/2019 - 01/2018
2Bone Marrow Transplantation (Transplantation, Bone Marrow)
04/2014 - 10/2010
1Extracorporeal Membrane Oxygenation
12/2021
1Renal Dialysis (Hemodialysis)
01/2020
1Resistance Training
01/2018